分类： health

In a groundbreaking study, researchers from Lanzhou University have unveiled the heart-protective properties of nicotinamide, a derivative of B vitamins, in the context of tumor treatment. Published in the journal *Science China: Life Sciences*, the research sheds light on the mechanisms behind early cardiotoxicity induced by immune checkpoint inhibitors, such as anti-programmed cell death protein 1 (PD-1), which are increasingly used in cancer immunotherapy. Led by Professor Bai Ming of Lanzhou University First Hospital, the study combined clinical data with experimental models to explore the role of PD-1 in cardiotoxicity and its underlying pathways. The team conducted randomized controlled trials to validate nicotinamide’s efficacy in preventing early cardiotoxicity linked to PD-1 therapy. Their findings revealed that nicotinamide, a clinically accessible drug, offers a safe and effective preventive strategy. This approach emphasizes early intervention, enabling the protection of heart function without compromising anti-tumor efficacy. Professor Bai highlighted the significance of the study in addressing safety concerns in cancer treatment, noting that nicotinamide could serve as a promising preventive measure against cardiac immune-related adverse events. The research underscores the potential for rapid clinical application, offering a synergistic treatment model that balances tumor control and heart health.

Health experts are urging for heightened public awareness and the dispelling of misconceptions to improve the coverage rate of the human papillomavirus (HPV) vaccine in China. HPV, a leading cause of cervical cancer, claimed 350,000 lives globally in 2022, with China accounting for 16% of these fatalities. Starting November 10, China will integrate the HPV vaccine into its national immunization program, offering free bivalent HPV vaccines to girls aged 13 and above born after November 10, 2011. This marks a significant shift from previous policies that targeted children under six, now extending to adolescents and focusing on preventing a malignant tumor caused by chronic infection, particularly in women. Du Heng of the Gates Foundation emphasized the long-term impact of this initiative, noting that full outcomes may take 20 to 30 years to manifest. As of June, 18 provincial-level regions in China have already provided free HPV vaccinations to about 5 million girls annually, targeting those aged 9 to 14. In Beijing, for instance, girls in the 7th grade and above can receive free domestically developed bivalent vaccines, which protect against the two most common HPV strains responsible for 70-80% of cervical cancers. Despite these efforts, some parents remain hesitant, citing concerns about the necessity and safety of the vaccine. However, experts like Qiao Youlin from Peking Union Medical College believe that these challenges are temporary and will improve with increased health awareness. The World Health Organization aims for 90% of girls globally to be fully vaccinated against HPV by the age of 15 by 2030, as part of its strategy to eliminate cervical cancer. In China, the free vaccination policy has already covered many eligible girls, showcasing significant progress. Experts also stress the importance of regular cervical cancer screenings and the role of men in HPV prevention, as their infection rate is as high as 45%, often without symptoms. Eliminating cervical cancer is seen as a shared societal responsibility, achievable through enhanced scientific awareness and collective action.

NMC Royal Hospital located in Khalifa City has been honored with the esteemed Comprehensive Chest Pain Center Certification by the American Heart Association (AHA). This recognition underscores the hospital’s commitment to delivering exceptional cardiac care and its adherence to rigorous international standards in diagnosing and treating chest pain. The certification process involved a thorough evaluation of the hospital’s protocols, facilities, and medical expertise, ensuring that patients receive timely and effective care for cardiac emergencies. This achievement positions NMC Royal Hospital as a leader in cardiovascular health within the region, enhancing its reputation as a trusted healthcare provider. The certification also reflects the hospital’s dedication to continuous improvement and patient safety, aligning with global best practices in cardiac care.

NMC Royal Hospital, located in Khalifa City, has achieved a significant milestone by receiving the Comprehensive Chest Pain Center Certification from the American Heart Association (AHA). This prestigious accreditation underscores the hospital’s commitment to delivering exceptional cardiac care and adhering to the highest standards in diagnosing and treating chest pain and related cardiovascular conditions. The certification process involved rigorous evaluation of the hospital’s protocols, facilities, and medical expertise, ensuring alignment with AHA’s stringent criteria. This recognition not only highlights NMC Royal Hospital’s advanced capabilities in cardiac care but also positions it as a leading healthcare provider in the region. The achievement is expected to enhance patient trust and attract individuals seeking top-tier medical services for heart-related issues.

NMC Royal Hospital – Khalifa City has been awarded the Comprehensive Chest Pain Center Certification by the American Heart Association (AHA), a globally recognized benchmark for excellence in cardiac care. This accolade underscores the hospital’s dedication to delivering safe, timely, and effective treatment for patients experiencing chest pain and other cardiac emergencies. The certification process involved a rigorous evaluation of the hospital’s adherence to evidence-based standards, advanced clinical protocols, and continuous quality improvement in chest pain management. By achieving this recognition, NMC Royal Hospital joins an elite group of healthcare institutions worldwide that provide top-tier emergency cardiac care. For patients, this certification translates to faster, life-saving interventions during critical moments. Chest pain is often the first indicator of a heart attack, and prompt treatment is essential to minimize heart muscle damage and enhance survival rates. The hospital’s multidisciplinary cardiac care team is trained to respond swiftly and efficiently, ensuring patients receive immediate diagnosis, expert treatment, and seamless care coordination. Families can rest assured that every stage of care, from emergency triage to specialized treatment, meets the highest international standards. Dr. Abdulla Al-Nakshabandi, Medical Director of NMC Royal Hospital – Khalifa City, emphasized the importance of this achievement, stating, “Early recognition of chest pain can save lives, and every minute counts in treating a heart attack. Our team’s timely and expert care ensures that every cardiac emergency receives the attention it deserves.” Beyond clinical expertise, this milestone reflects NMC Healthcare’s broader commitment to patient safety, innovation, and trust. The hospital has invested in cutting-edge technology, highly skilled cardiac specialists, and evidence-based practices to deliver exceptional care. It also highlights the hospital’s leadership in the UAE’s healthcare sector, contributing to national efforts to reduce the burden of cardiovascular disease, a leading cause of death globally. Additionally, the certification aligns with NMC’s mission to promote community health through education, prevention, and awareness. By emphasizing the importance of early recognition and treatment of chest pain, NMC Royal Hospital aims to empower individuals and families with life-saving knowledge.