分类: health

  • Norwegian effectively cured of HIV after transplant from brother

    Norwegian effectively cured of HIV after transplant from brother

    In a groundbreaking medical announcement made Monday, a 63-year-old Norwegian man has been pronounced functionally cured of HIV, marking one of the raiest and most hopeful breakthroughs in global HIV research in recent years. Dubbed the “Oslo patient,” he becomes the first person worldwide to achieve long-term HIV remission following a stem cell transplant from a related family member, joining a small group of fewer than 10 people globally who have reached this milestone after receiving transplants to treat concurrent blood cancer.

    The patient had lived with an HIV diagnosis since 2006, before receiving a devastating secondary diagnosis of myelodysplastic syndrome, a life-threatening blood cancer, in 2017. His care team at Oslo University Hospital launched a search for a suitable donor that could address both conditions, ultimately turning to the patient’s older brother when no matching unrelated donor with the required genetic trait was found. In a stunning twist of fate revealed on the day of the 2020 transplant, doctors discovered the brother unknowingly carried the rare CCR5Δ32 genetic mutation—an alteration that blocks HIV from entering and infecting human immune cells. Only 1% of northern European populations carry this rare protective mutation.

    “It was like winning the lottery twice,” lead study author Dr. Anders Eivind Myhre, of Oslo University Hospital, told Agence France-Presse. The case study detailing the achievement was published in the journal *Nature Microbiology*. Two years post-transplant, when the patient discontinued his daily antiretroviral therapy that had long kept his viral load suppressed, researchers found no trace of replicating HIV in samples of his blood, bone marrow, or intestinal tissue. “For all practical purposes, we are quite certain that he is cured,” Myhre confirmed. The patient, who has chosen to remain anonymous, is now thriving with abundant energy and reports enjoying a full, unrestricted life, according to his care team.

    Unlike the handful of prior cured HIV cases that relied on unrelated donor transplants, the Oslo case marks the first time a successful cure has been achieved with a family member donor. Study co-author Dr. Marius Troseid of the University of Oslo explained that the patient’s entire immune system has been fully replaced by the donor’s genetically resistant cells—a complete reconstitution that has been clearly documented in both his bone marrow and gut tissue for the first time in any cured HIV patient. Given his current excellent health, Troseid noted that the “Oslo patient” label may no longer fit: “The Oslo patient is perhaps no longer a patient. At least he doesn’t feel like it.”

    This achievement builds on a decades-long line of incremental breakthroughs, starting with the first ever declared HIV cure, that of Timothy Ray Brown, the “Berlin patient,” in 2008. Subsequent cases have since been reported in London, New York, Geneva, Düsseldorf, and other cities around the world, with one 2024 case even achieving long-term remission without a donor carrying two copies of the mutated CCR5 gene, expanding researchers’ understanding of what makes a cure possible.

    Crucially, experts stress that the high-risk, invasive stem cell transplant procedure remains only an option for the small subset of people living with HIV who also have a life-threatening blood cancer, making it completely unfeasible for the more than 38 million people globally living with HIV. Still, researchers remain optimistic that the insights gained from studying these rare, successful cases will deepen scientific understanding of how HIV persists in the body and pave the way for a widely accessible cure that can help all people living with the virus end their lifelong reliance on antiretroviral treatment.

  • Cambodia’s 72-year-old king says he has prostate cancer and is getting treatment in China

    Cambodia’s 72-year-old king says he has prostate cancer and is getting treatment in China

    PHNOM PENH, Cambodia – In a public announcement made Friday, 72-year-old Cambodian King Norodom Sihamoni confirmed that he has been diagnosed with prostate cancer during a recent medical visit and will receive all required treatment for the condition in China, where the diagnosis was first confirmed.

    The monarch’s statement, published to his official Facebook page and distributed nationwide by Cambodia’s state-run news agency AKP, notes that the cancer was detected during a scheduled health screening at a public Beijing hospital. Sihamoni and his 86-year-old mother, Queen Mother Norodom Monineath, traveled to the Chinese capital at the end of February for their annual routine health check-ups, a long-standing practice for the royal family.

    Notably, the king’s official message did not disclose details about the stage of his cancer or the specific treatment plan he will follow. Medical consensus shows that prostate cancer has a high survival rate when caught in early stages, with the American Cancer Society estimating that roughly one out of every eight men globally will receive a prostate cancer diagnosis at some point in their lifetimes.

    This diagnosis carries personal historical context for the Cambodian royal family: Sihamoni’s father, former King Norodom Sihanouk, was also diagnosed with prostate cancer back in 1993, and similarly traveled to China for ongoing medical care. Sihanouk ultimately lived to 89 years old, passing away in Beijing in 2012, nearly 20 years after his initial diagnosis.

    Sihamoni ascended to Cambodia’s constitutional throne in October 2004, just one week after his father’s voluntary abdication. As a constitutional monarch, his role is almost entirely ceremonial, and he has long maintained a deliberately low public profile across his nearly 20-year reign. Before taking the crown, he represented Cambodia as an ambassador to the United Nations Educational, Scientific and Cultural Organization (UNESCO), and gained early recognition as a trained classical ballet dancer. He currently remains unmarried and has no children.

  • Outbreak of measles kills 100 kids in Bangladesh

    Outbreak of measles kills 100 kids in Bangladesh

    A resurgent measles outbreak in Bangladesh has claimed the lives of approximately 100 children and triggered more than 7,500 suspected infections across the country, prompting health authorities to roll out an urgent mass immunization campaign targeting high-risk communities. Official data released ahead of the campaign launch on Sunday confirms the rapid spread of the vaccine-preventable disease, which had been on the brink of elimination in the South Asian nation for nearly two decades.

    The emergency campaign, inaugurated by Health and Family Welfare Minister Sardar Md Sakhawat Hossain at a public health facility near the capital Dhaka, will prioritize more than 1 million children aged six months to five years across 18 hard-hit districts that have recorded the highest infection rates. Following this targeted push, a national measles-rubella vaccination initiative will roll out to all remaining districts starting May 3, with 30 of the most severely affected localities already rolling out immunization services ahead of the official schedule.

    Discrepancies in official death figures reflect gaps in diagnostic access across the country: the ministry has confirmed 17 measles-linked deaths, with 113 additional suspected deaths. Of the total suspected infections, more than 6,400 are recorded in children under five, the age group most vulnerable to life-threatening complications from the disease. Public health officials note that most unconfirmed deaths occurred before patients could receive diagnostic testing, meaning the actual death toll is likely closer to the 100 suspected fatalities currently cited.

    “Compared with past years, the number of affected children is higher, and the death toll is higher too,” explained Halimur Rashid, director of Bangladesh’s Communicable Disease Control unit, in an interview with Agence France-Presse.

    Data from the World Health Organization (WHO) shows that Bangladesh saw its largest recorded measles outbreak in 2005, with nearly 26,000 suspected cases. After that peak, case numbers dropped steadily for nearly 20 years, hitting historic lows before the 2026 resurgence.

    Health experts point to a mix of interconnected factors that allowed the outbreak to take hold. Rashid cited systemic gaps including widespread vaccine shortages, while other public health leaders note that a scheduled 2024 national measles vaccination drive was delayed by widespread political unrest that ultimately led to the ouster of former Prime Minister Sheikh Hasina’s government.

    Officials add another layer of vulnerability: while the national immunization schedule recommends a first measles dose at nine months of age, a large share of the recent infections have occurred in infants as young as six months, who have not yet been scheduled for vaccination.

    Mahmudur Rahman, head of the National Verification Committee of Measles and Rubella, acknowledged that the country missed a key public health target set years prior: “We committed to reducing the number [of measles cases] to zero by December 2025 but failed to achieve the target due to poor vaccination programs.”

    Tajul Islam A. Bari, a former senior official with Bangladesh’s Expanded Programme on Immunization and a leading public health expert, said institutional missteps contributed directly to the crisis. “Although funds had been allocated for vaccine purchases, authorities had failed to procure them,” Bari explained. “Now we see the result — the situation is scary.”

    The Bangladesh outbreak aligns with a global trend of rising measles cases and deaths in recent years. The WHO’s latest 2024 global data estimates that as many as 95,000 people died from measles that year, the vast majority unvaccinated or under-vaccinated children under five.

    As defined by the WHO, measles is one of the most contagious viral diseases on Earth, spread through respiratory droplets when an infected person coughs or sneezes. While it can infect people of any age, it disproportionately affects young children and can cause severe life-threatening complications including brain swelling and acute respiratory distress. No targeted antiviral treatment exists for measles after infection, making preventive vaccination the only effective public health intervention to stop outbreaks.

  • Bangladesh conducts emergency measles vaccinations as outbreak kills more than 100 children

    Bangladesh conducts emergency measles vaccinations as outbreak kills more than 100 children

    A deadly measles outbreak that has claimed the lives of more than 100 children in less than a month has prompted Bangladesh to roll out an urgent immunization campaign, as public health authorities work to contain the fast-spreading infection. In a collaborative effort between the Bangladeshi government and global health partners including the World Health Organization (WHO), UNICEF, and Gavi, the Vaccine Alliance, the campaign began Sunday targeting children between 6 months and 5 years old across 18 high-risk districts. The initiative will expand to all regions of the country in phased stages starting next month, according to a joint official statement.

    As of mid-March, Bangladeshi health officials have recorded more than 7,500 suspected measles cases, with over 900 confirmed infections in the South Asian nation of 170 million people. Rana Flowers, UNICEF’s representative in Bangladesh, emphasized the organization’s deep alarm over the sharp surge in cases, which disproportionately endangers the country’s youngest and most medically vulnerable populations. “This resurgence highlights critical immunity gaps, particularly among zero-dose and under-vaccinated children, while infections among infants under nine months, who are not yet eligible for routine vaccination, are especially alarming,” Flowers said.

    Per WHO guidelines, measles is an extremely contagious airborne viral illness that triggers fever, respiratory distress, and a distinct full-body rash. The infection can lead to severe life-threatening complications, particularly for young children. Widespread vaccination is the only effective way to halt transmission, but WHO data notes that 95% population coverage is required to achieve herd immunity and stop sustained spread.

    Bangladesh’s current Health Minister Sardar Mohammed Sakhawat Husain told Parliament Monday that the current outbreak stems from systemic mismanagement and failures by previous administrations. He alleged that the ousted government of former Prime Minister Sheikh Hasina, followed by the interim administration led by Nobel Peace Prize winner Muhammad Yunus, failed to maintain adequate vaccine stockpiles, leading to shortages that affected measles vaccines and six other routine childhood immunizations. The ongoing immunization program was further disrupted by the country’s recent period of political upheaval: Hasina was removed from office in a mass popular uprising in 2024, and Yunus’s interim government only transferred power to a newly elected administration after February’s general election.

    Public health officials are now urging parents to seek immediate hospital care for any child showing suspected measles symptoms, warning against self-treatment with unregulated medications from local shopkeepers. F. A. Asma Khan, deputy director of Dhaka’s Infectious Diseases Hospital, stressed that any child experiencing a high fever above 38.3°C (101°F) should be evaluated by professional medical staff immediately. “Instead, they must take the child to a hospital as soon as possible, because our medical officers are capable of providing proper basic treatment,” Khan said.

    Bangladesh has made significant progress in childhood immunization over the past four decades: following the launch of a national mass immunization campaign in 1979, the country raised full immunization coverage from just 2% to 81.6% today. Still, UNICEF warned in a 2023 report that despite these gains, stark immunization disparities remain across different population groups and regions, leaving millions of children at risk of vaccine-preventable diseases like measles.

  • Emergency jabs after 100 children die of suspected measles in a month in Bangladesh

    Emergency jabs after 100 children die of suspected measles in a month in Bangladesh

    A devastating measles outbreak sweeping across Bangladesh has claimed more than 100 lives, the vast majority of them young children, since mid-March, prompting public health authorities to roll out an urgent mass vaccination campaign targeting the nation’s most vulnerable youth. Officials fear this outbreak could become the deadliest wave of the highly contagious airborne disease the country has seen in recent decades.

    Official data from Bangladesh’s Ministry of Health confirms that more than 7,500 suspected measles cases have been recorded since 15 March, with over 900 of those cases already laboratory-confirmed. Local media reports highlight just how dramatic this surge is: in all of 2025, Bangladesh recorded only 125 total confirmed measles cases.

    For decades, Bangladesh has run routine childhood immunization programs to protect against measles, but this sudden outbreak has laid bare critical gaps in the country’s vaccination infrastructure that have sparked widespread alarm among global and local public health experts.

    “Vaccines are foundational to child survival,” Rana Flowers, UNICEF’s representative in Bangladesh, said in an official statement released Sunday. “The current measles outbreak is putting thousands of children, especially the youngest and most vulnerable, at serious risk.”

    Under Bangladesh’s standard public health protocols, routine measles vaccination is administered to infants at nine months of age. But Shahriar Sajjad, deputy director of Bangladesh’s Health Department, told BBC Bangla that roughly one-third of all infected patients in the current outbreak are younger than nine months old – putting them outside the age eligibility for standard immunization before they were exposed.

    Flowers noted that infections among these too-young infants are “especially alarming” given their weaker immune systems and higher risk of life-threatening complications.

    Beyond routine annual vaccinations, Bangladesh has historically held targeted mass measles vaccination campaigns every four years to boost coverage and close immunity gaps. But those scheduled campaigns have been derailed by successive crises since 2020. Sajjad told BBC Bangla that the first disruption came from the global COVID-19 pandemic, followed by widespread domestic political unrest that delayed planning and execution.

    Bangladesh saw major political upheaval in 2024, when large-scale anti-government protests led to the ousting of long-serving prime minister Sheikh Hasina. An interim caretaker government governed the country until a new administration was elected in February 2026, creating months of political and administrative uncertainty that disrupted public health programming. A planned mass vaccination campaign that was scheduled for April 2026 never launched, Sajjad confirmed.

    The English-language Bangladeshi newspaper *Daily Star* also reported that procurement challenges have led to widespread shortages of routine vaccines, including measles doses, across the country. Many political observers and local stakeholders have blamed the former interim government, which oversaw the rollout of a new vaccine procurement system, for the current supply shortfalls. But UNICEF pushed back on framing the crisis as the result of a single failure, noting that measles resurgences almost always stem from accumulated gaps in immunization coverage over time, rather than one isolated error.

    “Bangladesh has a strong history of high immunisation coverage, but even small disruptions can lead to the gradual accumulation of immunity gaps over time,” the organization explained in its statement.

    Working alongside global health partners UNICEF and the World Health Organization (WHO), Bangladesh’s new government has now launched an emergency vaccination campaign targeting both measles and rubella – a milder disease that shares similar symptomatic traits with measles. The campaign launched Sunday, and will roll out across 30 high-risk sub-districts (called upazilas) nationwide, aiming to reach more than 1.2 million children between the ages of six months and five years.

    UNICEF confirmed that the emergency drive will prioritize children who have previously missed routine immunization doses, who face the highest risk of severe illness and life-threatening complications from the virus. Special focus is being placed on two high-risk, densely populated areas: Dhaka, the overcrowded national capital, and Cox’s Bazar, which hosts massive, crowded camps for Rohingya refugees fleeing violence in neighboring Myanmar.

    Beyond the vaccination push, national health authorities are also launching public education campaigns, distributing informative infographics to teach communities how to identify early measles symptoms and prevent further spread. Measles spreads easily through airborne respiratory particles, and can cause severe neurological complications, organ damage, and death even in previously healthy children. Common early symptoms include high fever, red watery eyes, sore throat, cough, and sneezing.

    Global public health data underscores the ongoing threat of measles worldwide. According to the WHO, an estimated 95,000 people died from measles globally in 2024, more than 90% of whom were children under five years old. The disease is entirely preventable through safe, effective vaccination, but herd immunity requires a 95% population vaccination rate to stop sustained community transmission.

    Over the past 20 years, global public health efforts drove a dramatic decline in global measles cases and deaths: total annual cases fell from 38 million in 2000 to 11 million in 2024, a 71% drop. But the WHO has repeatedly warned of a growing global resurgence as routine vaccination coverage dropped following the COVID-19 pandemic. A 2026 report in the medical journal *The Lancet* found that 2024 and 2025 saw the highest number of national measles outbreaks recorded worldwide in more than 20 years.

    Outbreaks have surged across parts of Asia, Africa, Europe, the United States, and the United Kingdom in recent years. In many Western nations, growing anti-vaccine skepticism that expanded during the COVID-19 pandemic has driven down vaccination rates below the herd immunity threshold. In February 2026, for example, a measles outbreak at multiple schools in north London prompted UK public health officials to issue an urgent reminder to parents to ensure their children are fully vaccinated.

  • ‘Wow!’ The eye surgery marathon that restored sight for some South Africans

    ‘Wow!’ The eye surgery marathon that restored sight for some South Africans

    In the South African township of Tsakane, 84-year-old Gladys Khoza had for years been separated from the simple joy of seeing her family — not due to travel restrictions or distance, but because age-related cataracts had robbed most of her vision. Today, that separation is over. Khoza is one of 133 South Africans who regained their sight during a two-weekend marathon of free cataract surgeries held at two regional hospitals near Johannesburg last month.

    When a nurse removed her post-operative bandage one day after the quick procedure, Khoza stared at the newly clear world around her and whispered in delighted disbelief, “Wow!” When the nurse asked if she could make out her form, Khoza replied with a wide grin, “Very well.”

    For Khoza, who faced total blindness in one eye and long-standing impairment in the other, the 15-minute routine surgery has transformed her daily quality of life. After months of longing, she can once again visit with loved ones, read her cherished Bible, and enjoy the late-night soap operas she loves — small pleasures millions of people take for granted.

    Cataracts, a condition where the eye’s natural lens becomes clouded over, is the world’s leading cause of curable blindness, most commonly affecting older adults. The straightforward surgery replaces the clouded lens with an affordable artificial implant, permanently restoring vision. Yet for patients relying on South Africa’s public health system, even this simple procedure can require years-long waits on official waiting lists. Many of the patients selected for this month’s surgical marathon had been waiting for clear vision since 2019.

    For Dr. Tebogo Fakude, one of the volunteer ophthalmologists who participated in the initiative, the work carries deep personal meaning: his own mother lived with blindness before her passing. “Restoring sight is beautiful,” he explained. “It doesn’t just fix a person’s eyes — it alleviates the depression that comes with losing your vision, and it eases the constant feeling that you are a burden to your loved ones.”

    Global health data underscores the scale of unaddressed need for this life-changing care. According to the World Health Organization (WHO), more than 2 billion people worldwide live with some form of vision impairment, and half of those cases could be prevented or corrected with accessible treatment. Of the nearly 100 million people globally living with operable cataracts, half still lack access to the surgery they need. A March 2026 study published in *The Lancet* found that the gap is far wider in Africa, where 75% of people with cataracts never receive corrective surgery.

    In South Africa, backlogged elective surgery has emerged as a major public health challenge. Government-run public hospitals serve more than 75% of the country’s 62 million residents, but stretched resources force facilities to prioritize emergency and life-saving procedures over routine elective care like cataract removal. Currently, South Africa has a national backlog of more than 240,000 people waiting for cataract surgery, with more than 35,000 people living with cataract-related blindness in Gauteng province alone — the country’s most populous region, where the recent surgery marathon was held. The country sees roughly 300,000 new cataract diagnoses each year, according to Fakude.

    To chip away at this growing backlog, South Africa’s Department of Health launched targeted surgical marathons, first held on Nelson Mandela International Day in 2023 to honor the legacy of the country’s first Black democratic president. The initiative has since grown into an ongoing public-private partnership that hosts multiple events annually, focused on clearing backlogs for different high-need procedures. Past marathons have addressed prostate conditions, cleft palate repairs, and gastric issues, with cataracts selected as the latest priority given the scale of unmet need.

    During the recent cataract event, teams of volunteer surgeons worked at a steady pace to treat as many patients as possible. At Pholosong Regional Hospital, a new patient entered the operating theater roughly every 30 minutes, with soothing gospel music playing over speakers to keep the medical team focused and energized. At peak times, two surgeons operated concurrently to speed up the flow of procedures. Surgeons made tiny incisions through a surgical microscope, removed the clouded lens, and inserted the new artificial implant — all in less than 20 minutes per patient. By the end of the two weekends, the team had completed 133 procedures, including 60 on the final weekend alone.

    Seventy-two-year-old Molefe Mokoena, who had lived with cataracts for four years before his surgery, shared the widespread excitement among patients. “I want to see my great-grandchildren,” he said. “I want to drive my car again, and I’m just so happy about this second chance.”

    The WHO classifies cataract surgery as one of the most cost-effective medical interventions in global health, noting that it does not just restore vision — it restores patients’ independence, dignity, and access to economic and social opportunities. South African health officials have pledged to expand the surgical marathon model to continue clearing backlogs and expand access to life-changing care for low-income and public health patients across the country.

  • Turkish woman makes remarkable recovery at Chongqing hospital

    Turkish woman makes remarkable recovery at Chongqing hospital

    A 47-year-old Turkish woman living and working in Southwest China’s Chongqing has made an extraordinary full recovery from aggressive diffuse large B-cell lymphoma after receiving personalized, multidisciplinary care at a leading local public hospital, a case that showcases the high quality of China’s international medical services for foreign residents.

    Going by the pseudonym Zeynep, the patient was first admitted to the Hematology Department of the First Affiliated Hospital of Chongqing Medical University on December 31, 2024, presenting with a severe case of the blood cancer marked by widespread lymph node involvement. Medical teams moved quickly to run diagnostic tests, confirming the diagnosis and flagging the urgent need for immediate therapeutic intervention. By the beginning of January 2025, Zeynep’s condition deteriorated rapidly, triggering life-threatening acute respiratory failure that required intensive care support.

    Faced with the serious health crisis, Zeynep and her family initially planned to travel back to Turkiye to complete treatment, a common choice for many foreign expats facing major illness abroad. But after receiving positive feedback and endorsement of the Chongqing hospital’s proposed treatment plan from medical experts in Turkiye, the family chose to stay and proceed with care in China.

    To deliver the best possible outcome for Zeynep, the hospital assembled a cross-departmental multidisciplinary treatment team drawing specialists from eight clinical and research units, including pathology, clinical molecular diagnosis, and critical care medicine. This collaborative approach allowed clinicians to address every complication of Zeynep’s case and adapt treatment to her specific health profile.

    According to Zhang Hongbin, chief physician in the hospital’s Hematology Department and lead of Zeynep’s care team, clinicians implemented a customized first-line regimen called Pola R-CHP, which integrates multiple targeted cancer therapies. Unlike standard treatment protocols, this personalized approach is designed to boost long-term survival outcomes for patients with high-risk diffuse large B-cell lymphoma. Zhang explained that the tailored therapy is projected to raise the patient’s five-year survival rate from the 60 percent average associated with traditional regimens to 80 percent. After weeks of coordinated care, Zeynep achieved a remarkable recovery that has been hailed as a testament to China’s advancing precision oncology capabilities and patient-centered care for international residents.

  • Congo says its mpox outbreak is over after 2 years and more than 2,200 suspected deaths

    Congo says its mpox outbreak is over after 2 years and more than 2,200 suspected deaths

    CAPE TOWN, South Africa – After two years of widespread transmission that claimed thousands of lives, the Democratic Republic of Congo (DRC) formally announced the end of its devastating mpox outbreak on Thursday, lifting the classification of the virus as a national public health emergency.

    Congolese Health Minister Roger Kamba confirmed the declaration to reporters, stating that national health authorities had formally determined the outbreak had been brought under control. The central African nation bore the brunt of a resurgent mpox wave that emerged in 2024, with transmission spilling across DRC’s borders into neighboring countries and prompting the World Health Organization (WHO) to declare the event a global health emergency that same year. The WHO rolled back that global emergency designation in September 2024.

    Data from the Africa Centers for Disease Control and Prevention (Africa CDC) shows that between 2024 and 2025, the DRC recorded more than 161,000 suspected mpox cases, with approximately 37,000 of those cases confirmed via laboratory testing. Across the outbreak, 2,286 deaths were suspected to be linked to mpox, though only 127 of those fatalities were verified through diagnostic testing.

    First documented by researchers in 1958, when pox-like lesions were observed in research monkey colonies, mpox (formerly called monkeypox) long remained a rare zoonotic infection restricted largely to central and West Africa. For decades, nearly all confirmed human cases occurred in people who had close direct contact with infected wild animals.

    That epidemiological pattern shifted dramatically in 2022, when scientists confirmed for the first time that mpox could spread through close sexual contact. That discovery came as the virus sparked unexpected outbreaks across more than 70 countries that had never previously reported sustained local mpox transmission, triggering a global public health response.

    According to WHO guidance, the most prevalent symptoms of mpox infection include the development of a characteristic rash and fever, though the virus can cause severe complications in vulnerable populations in some cases. The vast majority of infected people eventually make a full recovery with appropriate care.

    This reporting is part of AP News’ Africa Pulse coverage, supported by a grant from the Gates Foundation. The Associated Press maintains full editorial independence over all its content, with public transparency standards for philanthropic partnerships available on AP.org.

  • Isotope production unit boosts cancer care

    Isotope production unit boosts cancer care

    China has marked a transformative milestone in advancing domestic cancer care, with researchers at the China Spallation Neutron Source (CSNS) in Dongguan, Guangdong province announcing they have achieved full capability to produce life-saving alpha-emitting medical isotopes. For years, China has relied on costly, supply-volatile imports of these critical materials, creating a major bottleneck in access to cutting-edge cancer treatment. The new domestic production capacity is set to resolve this gap, bringing next-generation targeted cancer therapy within reach for far more patients.

    Called the “nuclear warheads” of modern oncology, alpha isotopes are the core component of next-generation radiopharmaceuticals that deliver lethal radiation directly to tumor cells while minimizing damage to surrounding healthy tissue. The CSNS team has confirmed it can produce three of the most clinically essential alpha isotopes: radium-223, actinium-225, and lead-212, all of which have well-documented effectiveness in treating hard-to-manage late-stage prostate cancer and neuroendocrine tumors.

    Wang Sheng, director of the Spallation Neutron Source Science Center and a professor at the Chinese Academy of Sciences’ Institute of High Energy Physics, emphasized the urgent public health need for this advancement, noting that China records nearly 5 million new cancer diagnoses annually — accounting for 25% of the global total — with an overall mortality rate above 50%.

    Unlike conventional radiation therapy, which uses long-range radiation that can pass through healthy tissue and cause unintended damage, alpha particles function like precision short-range heavy artillery. Once inside a cancer cell, alpha radiation releases enough energy to break both strands of the cell’s DNA, creating irreversible damage that the cell cannot repair. Wang added that the treatment also delivers a valuable “bystander effect”: dying cancer cells release signals that trigger the death of adjacent malignant cells, even if those cells were not directly targeted by radiation.

    Historically, medical alpha isotopes have been produced almost exclusively in nuclear reactors. But the CSNS research team developed an innovative alternative approach using a high-energy linear accelerator. By directing a high-powered proton beam at a target constructed from thorium, a naturally occurring abundant metal, researchers are able to extract the exact isotopes required for clinical use.

    Dai Xiongxin, who leads the project’s industrialization initiative, explained that this new production method offers multiple advantages over traditional reactor-based production. It eliminates the need for highly enriched uranium, a material that carries inherent nuclear proliferation risks, making the process both safer and more cost-effective. “It offers flexible production capacity, broader access to raw materials, and significantly lower costs,” Dai noted.

    Rigorous quality testing has confirmed that the domestically produced isotopes achieve a purity level of over 99%, matching the high quality standard of imported international supplies. The project does face one key logistical challenge, however: alpha isotopes have extremely short half-lives, decaying within days or even hours of production, making long-term storage and long-distance transportation impossible. To overcome this barrier, the CSNS center signed a strategic cooperation agreement with the China Isotope & Radiation Corporation over the weekend to build a complete localized industrial chain for production and distribution in Guangdong province.

    A purpose-built dedicated production line is currently under construction at the site. Once the facility reaches full operational capacity by 2031, it is projected to produce enough isotopes to supply nearly 1 million patient treatments per year, marking a major leap forward in China’s quest for self-sufficiency in advanced medical resources and expanding access to life-saving cancer care across the country.

  • Africa calls for stronger health system to curb preventable maternal, child deaths

    Africa calls for stronger health system to curb preventable maternal, child deaths

    African health authorities are sounding the alarm over what they describe as a ‘silent crisis’ of preventable maternal and child mortality across the continent. Current statistics reveal devastating hourly losses: approximately 50 mothers, 140 newborns, and 300 children under five perish from largely preventable causes, according to data from the Africa Centres for Disease Control and Prevention.

    Jean Kaseya, Director-General of the Africa CDC, characterized the situation as not merely a health issue but a fundamental development and sovereignty challenge. ‘A continent that cannot protect its mothers and children cannot claim full sovereignty over its future,’ Kaseya stated, emphasizing the need for transformative reforms in healthcare delivery systems.

    The crisis stems from persistent systemic failures including delayed care, financial barriers, and fragmented health infrastructure. Kaseya identified significant inefficiencies in health financing, with an estimated 40 percent of health expenditure lost due to weak procurement systems, poor planning, lack of accountability, and the presence of ghost workers.

    Kenyan health officials echoed these concerns, with Cabinet Secretary Aden Duale acknowledging that maternal mortality, newborn deaths, and stillbirths remain unacceptably high despite progress in some areas. Duale called for accelerated action and warned against complacency in addressing these preventable tragedies.

    Digital innovation emerges as a promising solution pathway, with countries like Kenya implementing real-time data platforms to track health coverage and identify at-risk populations. Patrick Amoth, Director-General at Kenya’s Ministry of Health, emphasized the need to scale up evidence-based interventions including improved antenatal services, prevention of postpartum hemorrhage, and respectful maternity care.

    Health leaders unanimously called for a shift from donor-dependent models to coordinated, self-reliant healthcare systems capable of delivering equitable and sustainable care across the continent, particularly in rural and low-income communities where disparities remain most pronounced.