In an extraordinary medical achievement, a two-month-old Pakistani infant has successfully overcome a life-threatening congenital immune disorder following an emergency bone marrow transplant procedure in Abu Dhabi. The breakthrough case at Yas Clinic Khalifa City represents a significant advancement in pediatric critical care methodologies.
The infant, identified as Ayra, arrived at the facility in critical condition after weeks of unsuccessful treatment at another hospital. Medical examinations revealed she was combating three simultaneous severe infections while showing signs of organ stress and requiring medication to sustain blood pressure. This medical crisis stemmed from a rare congenital immunodeficiency that left her without natural infection-fighting capabilities.
Dr. Mansi Sachdev, Clinical Lead and Consultant of Paediatric Haematology, Oncology and Bone Marrow Transplant, explained the unprecedented challenges: ‘The conventional treatment protocol involving chemotherapy was not viable due to her critically compromised condition. Our only recourse was to perform an immediate transplant without standard preparatory procedures, relying entirely on her father’s healthy stem cells to combat the infections.’
The medical team discovered the infant’s father was a complete HLA (Human Leukocyte Antigen) match, enabling the high-risk procedure. This surgical intervention is considered exceptionally rare in pediatric medicine due to its inherent risks when performed without standard chemotherapy preparation.
Two months post-transplant, medical staff report remarkable progress. Ayra is now breathing independently, feeding normally, and has successfully cleared all three viral infections. The medical team anticipates her imminent discharge from the facility.
Dr. Maysoon Al Karam, Chief Medical Officer, emphasized the broader implications: ‘This case demonstrates the critical importance of early diagnosis and coordinated multidisciplinary care. The successful outcome illustrates what timely intervention and specialized medical management can achieve even with extremely fragile patients.’
The family’s medical history revealed they had previously lost another daughter to a similar undiagnosed condition at eighteen months old, highlighting the significance of this medical breakthrough for families dealing with rare immunological disorders.