The Africa Centres for Disease Control and Prevention (Africa CDC) has introduced the African Manufacturing Market Intelligence & Network Analysis (AMMINA) platform, a groundbreaking initiative designed to enhance health manufacturing, innovation, and self-reliance across the continent. Launched during the African Healthcare Manufacturing Trade Exhibition and Conference in Accra, Ghana, the platform aims to bolster health sovereignty and reduce Africa’s dependency on imported medical supplies. Jean Kaseya, Director-General of Africa CDC, emphasized that AMMINA will provide comprehensive data on manufacturers, production capacities, product portfolios, and market trends, enabling informed decision-making and fostering industrial growth. Initially, the platform maps data from over 700 manufacturers and 2,500 health products across 18 African Union (AU) Member States, with plans to expand coverage to all 55 Member States. AMMINA is expected to stimulate intra-African trade, attract sustainable investments, and drive innovation in local production of vaccines, medicines, and diagnostics. Africa CDC, in collaboration with AU institutions and partners, envisions AMMINA as a pivotal tool to unlock Africa’s manufacturing potential and secure the continent’s health future. This initiative comes as African nations strive to build a resilient health ecosystem, particularly in the wake of the COVID-19 pandemic, which highlighted vulnerabilities in global supply chains.