The quest for Middle East peace has been a recurring theme in U.S. presidential history, with several leaders attempting to broker breakthroughs before Donald Trump’s era. Bill Clinton’s ambitious peace plan, which aimed to resolve the Israeli-Palestinian conflict, was tragically derailed by the assassination of Israeli Prime Minister Yitzhak Rabin in 1995. This pivotal moment not only halted progress but also underscored the fragility of peace negotiations in the region. Other U.S. presidents, including Jimmy Carter and George H.W. Bush, also sought to mediate peace agreements, each facing unique challenges and setbacks. Carter’s Camp David Accords in 1978 marked a significant achievement, establishing a framework for peace between Israel and Egypt. However, subsequent efforts often faltered due to deep-seated animosities and shifting political landscapes. These historical attempts highlight the complexities of Middle East diplomacy and the enduring challenges faced by U.S. leaders in their pursuit of lasting peace.