标签: Europe

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  • Moderna says FDA refuses its application for new mRNA flu vaccine

    Moderna says FDA refuses its application for new mRNA flu vaccine

    In a significant regulatory development, Moderna announced Tuesday that the U.S. Food and Drug Administration has declined to review the company’s application for an innovative mRNA-based influenza vaccine. The decision represents the latest indication of intensified FDA oversight under Health Secretary Robert F. Kennedy Jr., who has consistently expressed skepticism toward mRNA technology both before and after assuming his current position.

    The FDA issued a ‘refusal-to-file’ letter citing concerns about Moderna’s clinical trial design, which involved 40,000 participants comparing the new vaccine against a standard flu shot. While the study demonstrated superior efficacy in adults aged 50 and older, FDA vaccine director Dr. Vinay Prasad determined the application lacked an ‘adequate and well-controlled trial’ because it didn’t compare the vaccine to ‘the best-available standard of care in the United States at the time of the study.’

    According to Moderna, FDA officials under the Biden administration had provided 2024 guidance indicating that while another brand specifically recommended for seniors would be preferable for participants aged 65 and older, the company’s chosen standard-dose vaccine remained acceptable. Moderna proceeded with the original study design with FDA’s conditional approval.

    The company emphasized that the FDA identified no specific safety or efficacy concerns with their product and noted they had submitted additional data from a separate trial comparing the vaccine against a licensed high-dose shot for elderly patients. Moderna CEO Stephane Bancel stated the decision ‘does not further our shared goal of enhancing America’s leadership in developing innovative medicines.’

    This regulatory action occurs against a backdrop of significant policy shifts under Kennedy’s leadership, including the rollback of COVID-19 shot recommendations, additional warnings for leading mRNA COVID vaccines, and the removal of administration critics from FDA advisory panels. Kennedy previously announced the cancellation of over $500 million in contracts and funding for mRNA vaccine development.

    The refusal marks a departure from decades of FDA practice allowing vaccine manufacturers to update annual flu shots based on immune response data rather than long-term efficacy studies. Prasad’s internal memo last year indicated this streamlined approach would no longer be permitted, prompting criticism from more than a dozen former FDA commissioners.

    Moderna has requested an urgent meeting with the FDA while pursuing regulatory approval for the vaccine in Europe, Canada, and Australia.

  • Olympic host Italy avoids NHL players but still brings in foreign hockey help

    Olympic host Italy avoids NHL players but still brings in foreign hockey help

    MILAN — The Italian Olympic hockey team competing on home ice represents a unique fusion of international talent united by ancestral roots. Unlike many host nations that recruit established NHL stars with distant heritage connections, Italy has constructed its roster primarily from homegrown players supplemented by North American professionals who have embraced their Italian lineage through years of national team commitment.

    Dustin Gazley, a 37-year-old Michigan native who once shared practice ice with Alex Ovechkin, exemplifies this journey. After extensive professional experience in the ECHL and AHL, Gazley secured Italian citizenship during high school and now celebrates his decision to bring his skills to Bolzano in the Italian Alps. “I haven’t looked back,” Gazley reflected on his European transition.

    The team’s composition includes two U.S.-born players, eight from Canada, and one from Sweden, all having obtained Italian passports through familial connections. Thomas Larkin, born in London to an Italian mother and American father, described the squad as “a melting pot for sure—we are all proud to be Italian,” noting how this diversity reflects Italy’s historical identity.

    Eligibility requirements mandated that heritage players spend two years with the national team before Olympic participation. Nick Saracino, a 33-year-old St. Louis native, acknowledged the uncertainty: “I knew Italy was hosting an Olympics… but didn’t know if I was going to be able to make the team as I was getting older.”

    The women’s team similarly integrates international talent, featuring five Americans and three Canadians. Calgary native Gabriella Durante’s goalkeeping performance secured Italy’s historic advancement to the quarterfinals.

    For many players, representing Italy fulfills deep cultural connections. Amie Varano from Massachusetts, whose family originated from Calabria, expressed: “I’ve always been proud of my Italian heritage… it was just like this proud feeling that I could someday represent this amazing country on the world stage.”

    Despite the current reliance on heritage players, Larkin envisions a future where Italy’s domestic development system eliminates the need for foreign reinforcements. “The dream is always to stay here and to make the place where you are at better,” he stated, while acknowledging the current value of committed international players: “if guys are proud to wear these colors and the blood runs Italian, that’s good with me.”

  • Campaigner ‘devastated’ over Donegal-Dublin flight changes

    Campaigner ‘devastated’ over Donegal-Dublin flight changes

    A contentious decision by the Irish government to alter the Donegal-Dublin flight route has ignited significant criticism from patient advocacy groups who fear devastating consequences for cancer patients requiring medical transportation. The newly announced Public Service Obligation (PSO) contract, awarded through competitive tender, eliminates afternoon flights and removes overnight aircraft placement in Donegal—changes that campaigners argue will severely disrupt vital medical travel arrangements.

    Mary Coyle of Donegal Cancer Flights and Services expressed profound dismay at the announcement, characterizing the decision as devastating for patients who rely on same-day round trips for critical cancer treatments. Despite widespread opposition evidenced by a 15,000-signature petition, the Department of Transport proceeded with the schedule modifications set to take effect March 29, 2026.

    The restructured service will maintain twice-daily return flights between Donegal and Dublin with international connections, preserving the early morning departure from Donegal and evening return from Dublin that many medical patients depend on. However, the elimination of afternoon flights and the change in aircraft overnight arrangements have raised alarms about forced overnight stays and exhausting alternative journeys for vulnerable passengers.

    Donegal Airport officials, notified of the contract decision on Tuesday, expressed concerns that the new arrangement fails to maximize regional connectivity and contradicts the fundamental purpose of PSO routes. The airport board is currently seeking legal advice regarding the changes, particularly objecting to the aircraft overnight policy that had provided reliability for time-sensitive travelers for 21 consecutive years.

    The Department of Transport maintains that the new contract demonstrates governmental commitment to northwest connectivity and stated it will closely monitor the new schedule’s performance during a three-month evaluation period. Meanwhile, campaigners plan to proceed with delivering their petition to Minister Darragh O’Brien, asserting that Donegal residents once again feel marginalized by centralized decision-making that overlooks regional healthcare necessities.

  • King Charles III seeks ‘moral high ground’ with pledge to help police as Epstein scandal deepens

    King Charles III seeks ‘moral high ground’ with pledge to help police as Epstein scandal deepens

    LONDON — In a dramatic departure from royal tradition, King Charles III has initiated an unprecedented response to the escalating scandal surrounding his brother Andrew Mountbatten-Windsor’s association with convicted sex offender Jeffrey Epstein. This modern monarchy approach contrasts sharply with historical practices where such controversies would typically be concealed through private arrangements.

    The royal transformation began in October when Charles systematically dismantled his brother’s royal status, revoking his princely title, evicting him from his 20-year residence at Royal Lodge, and issuing a formal statement expressing solidarity with Epstein’s victims. The palace’s commitment reached its zenith this week with Buckingham Palace’s groundbreaking announcement of full cooperation with any potential police investigation into Andrew’s connections with the financier.

    This royal accountability stems from the U.S. Justice Department’s release of millions of Epstein documents that detailed Andrew’s ongoing relationship with Epstein despite his 2008 conviction for soliciting a minor. Particularly damaging are allegations that Andrew shared confidential reports from his 2010 Southeast Asia trade mission with Epstein.

    Thames Valley Police confirmed Monday they are ‘assessing’ these recent allegations, prompting the palace’s immediate response. ‘The King has made clear, in words and through unprecedented actions, his profound concern at allegations which continue to come to light,’ the palace stated, emphasizing their readiness to support police inquiries.

    Constitutional monarchy expert Craig Prescott of Royal Holloway University notes these actions represent a strategic containment effort to isolate Andrew while protecting the institution’s integrity. Despite the damage to Andrew’s reputation, Prescott suggests the monarchy itself remains relatively secure if the scandal remains contained.

    The current crisis has been building since 2010 when Virginia Giuffre first accused Epstein of arranging her sexual encounter with Andrew when she was 17. The situation intensified with Andrew’s disastrous 2019 BBC interview where he showed poor judgment and lack of empathy for victims. While Queen Elizabeth initially removed Andrew from royal duties, Charles has taken more decisive action since ascending the throne.

    Historian Ed Owens, author of ‘After Elizabeth: Can the Monarchy Save Itself?’, observes that Charles’s approach reflects modern democratic expectations of accountability. ‘The monarchy is signaling very clearly that it recognizes that public opinion demands that justice be served,’ Owens noted, acknowledging that while this cooperation may generate unwanted headlines, it represents necessary demon-exorcising for the institution’s future.

  • French former teacher charged with abusing 89 teens dating back to 1960s

    French former teacher charged with abusing 89 teens dating back to 1960s

    French authorities have taken the extraordinary step of publicly identifying 79-year-old Jacques Leveugle, currently in custody in southeastern France, to facilitate victim identification in a sprawling sexual abuse case spanning six decades and multiple continents. The Grenoble prosecutor’s office revealed that Leveugle faces charges involving 89 teenage victims, with offenses allegedly occurring between 1967 and 2022 across numerous countries including France, Germany, Switzerland, Morocco, Niger, Algeria, the Philippines, India, Colombia, and New Caledonia.

    The breakthrough in this decades-long investigation came in October 2023 when Leveugle’s nephew, harboring suspicions about his uncle, discovered a USB drive containing what prosecutor Etienne Manteaux described as “15 volumes of exceptionally dense material” – including photographs and detailed written accounts of sexual encounters with minors aged 13 to 17. This evidence led to Leveugle’s arrest in 2024 while visiting family in the Isère region near Grenoble.

    Manteaux explained the unusual decision to publicly name the suspect: “Of the 89 assaults documented, we have only identified approximately 40 victims. The appeal for additional victims to come forward is crucial as many entries in his journal contain only first names, creating significant identification challenges.”

    The investigation reveals Leveugle operated as an informal educator and holiday camp assistant throughout his adult life, using his position to gain access to vulnerable teenagers. “Victims describe how he devoted considerable time to helping them learn foreign languages and develop cultural awareness,” Manteaux noted, describing the suspect as possessing “a complex personality.”

    In a disturbing development, Leveugle has allegedly confessed to two historic murders during interrogation. He claims to have suffocated his cancer-stricken mother in 1974 and his 92-year-old aunt in 1992, explaining that he hoped someone would show him similar “mercy” if he faced comparable end-of-life circumstances. A separate judicial investigation has been initiated regarding these admissions.

    Legal complications arise from France’s statute of limitations, which prevents prosecution for alleged assaults occurring before 1993. However, authorities emphasize the importance of establishing a complete historical record of Leveugle’s activities. This case follows patterns seen in other high-profile French sexual assault investigations where meticulous record-keeping by offenders ultimately contributed to their convictions, similar to the Pélicot and Le Scouarnec cases that resulted in 20-year prison sentences.

  • Italy takes bronze in mixed doubles curling as the US and Sweden battle for gold

    Italy takes bronze in mixed doubles curling as the US and Sweden battle for gold

    CORTINA D’AMPEZZO, Italy — In a dramatic conclusion to the mixed doubles curling competition, Italian athletes Stefania Constantini and Amos Mosaner captured the bronze medal with a decisive 5-3 victory over Great Britain on Tuesday. The match, held before a passionate home crowd, delivered an emotional outcome for both teams involved.

    The Italian pair, who entered the tournament as defending Olympic champions, demonstrated exceptional precision with their throws, ultimately thwarting the British duo’s strategy. For Constantini, a native of Cortina d’Ampezzo, the victory held special significance as she solidified her status as a local hero, celebrated by supporters who filled the stadium throughout the competition.

    Conversely, the British team of Jennifer Dodds and Bruce Mouat faced profound disappointment. Having concluded the round-robin stage with the highest number of wins, they were widely anticipated to advance to the gold medal match. Their departure from the ice was visibly dejected following the unexpected defeat.

    The stage is now set for an unprecedented championship final between the United States and Sweden. The American pair, Cory Thiesse and Korey Dropkin—popularly known as ‘Cory and Korey’—have already secured a historic achievement by becoming the first US athletes to medal in Olympic mixed doubles curling. Thiesse additionally earns the distinction of being the first American woman to claim an Olympic medal in the discipline.

    They will compete for the gold medal against Sweden’s sibling duo, Isabella and Rasmus Wranå, ensuring a thrilling conclusion to the mixed doubles curling event at the Winter Games.

  • Take a ride across frozen sea on Estonia’s ice road

    Take a ride across frozen sea on Estonia’s ice road

    A remarkable natural phenomenon has emerged in northern Europe as exceptionally low temperatures enabled the opening of a 20-kilometer (12.5-mile) ice road across frozen Baltic Sea waters, connecting Estonia’s two largest islands. The officially sanctioned route between Saaremaa and Hiiumaa islands commenced operations Sunday afternoon, with queues of vehicles eagerly awaiting passage.

    The decision to formalize the ice crossing came after local residents began spontaneously traversing the frozen sea despite significant safety risks. Ferry services had encountered substantial difficulties maintaining regular operations amid sustained subzero temperatures reaching minus 10 degrees Celsius (14°F). For Hiiumaa’s 9,000 residents, this frozen passage provides vital access to Saaremaa’s larger population center of 31,000 people for essential services including shopping, education, and mainland connections.

    Hiiumaa Mayor Hergo Tasuja emphasized that while practical necessity drove the road’s establishment, ice travel remains deeply embedded in regional culture. “For generations, local people who live here, especially those near the sea, swim and use boats in summer,” Tasuja explained. “In winter, it’s in their blood to go to the sea and step out on the ice.”

    Construction company Verston Eesti, responsible for road maintenance, implements rigorous safety protocols. Teams measure ice thickness every 100 meters, requiring minimum 24 centimeters (9.5 inches) of solid ice for vehicle passage. Workers continuously smooth over ridged surfaces and monitor weather conditions around the clock, adjusting the route as needed.

    Strict regulations govern ice road usage: vehicles cannot exceed 2.5 tons, must maintain either below 20 kph or between 40-70 kph speeds to prevent dangerous vibrations, and must keep safe distances without stopping. Unconventional safety measures include prohibited seatbelt use and requirements for easily openable doors to facilitate rapid evacuation if necessary.

    This marks the first successful ice road connection between the islands in approximately eight years, following a period of unusually warm winters that prevented safe freezing conditions. Verston Eesti has received additional contracts to establish two more ice routes connecting mainland Estonia to smaller islands this week.

  • Klaebo’s Olympic evolution leaves ski competitors in awe of Norwegian star

    Klaebo’s Olympic evolution leaves ski competitors in awe of Norwegian star

    TESERO, Italy — Norwegian cross-country skiing sensation Johannes Hoesflot Klaebo delivered another masterclass performance on Tuesday, securing his second Olympic gold medal at the Milan Cortina Winter Games with a commanding victory in the classic sprint event. The 29-year-old champion demonstrated unparalleled technical prowess and strategic brilliance throughout both preliminary rounds and the final race.

    Klaebo now stands just one medal shy of the Winter Olympics all-time record of eight gold medals, currently shared by three retired Norwegian legends from cross-country skiing and biathlon. With an existing collection of five golds, one silver, and one bronze from previous Winter Olympics in Beijing and Pyeongchang, Klaebo has evolved from a specialist sprinter into a complete cross-country dominator, recently claiming his first distance race victory in Sunday’s skiathlon.

    What distinguishes Klaebo from his competitors is a unique combination of explosive finishing power and breathtaking hill-climbing speed. During Tuesday’s race in northern Italy’s Tesero region, his brutal ascent on the final hill created an insurmountable gap that left other elite athletes struggling in his wake.

    Norwegian coach Ole Haldor Ensrud, currently working with South Africa’s Olympic team, explained to AP: ‘He has elevated the technical aspects of the sport to unprecedented levels while maintaining exceptional endurance fitness. His remarkable flexibility allows constant technique adaptation to varying terrains—a critical advantage in skiing that doesn’t exist in sports like running.’

    Fellow competitors acknowledge racing against Klaebo often means competing for second place. U.S. silver medalist Ben Ogden stated: ‘I approach every race believing victory is possible, but currently, many events become competitions for silver. I take pride in securing second place against such phenomenal talent.’

    Klaebo’s comprehensive skillset resulted from relentless training and meticulous race preparation. His summer training regimen included intensive roller-ski sessions in Park City, Utah, developing the technical versatility that now allows him to maintain speed across varying conditions while offering opponents few opportunities to challenge his dominance.

    The Norwegian champion admitted: ‘I maintain high personal expectations. Competing on familiar tracks where I understand my capabilities provides confidence. We’ve prepared thoroughly, and it’s rewarding to see that preparation translate to success.’

    After establishing an unbeatable lead on Tuesday’s final climb, Klaebo comfortably coasted to the finish, smiling and waving to spectators that included family members. Back in Norway, where cross-country skiing commands prime-time attention, Prime Minister Jonas Gahr Stoere immediately celebrated online: ‘What an athlete! Johannes Hoesflot Klaebo remains virtually unbeatable in sprint events. Congratulations!’

    A national sporting icon featured on billboards and television commercials throughout Norway, Klaebo recently became the subject of a feature documentary released in Norwegian cinemas last December. Despite approaching historic Olympic milestones, the champion remains focused on appreciating his current success: ‘I’m genuinely enjoying this experience. These are amazing moments to cherish.’

  • How Mandelson appointment nearly cost Starmer his job as UK prime minister

    How Mandelson appointment nearly cost Starmer his job as UK prime minister

    British Prime Minister Keir Starmer is confronting the most severe leadership crisis of his premiership following his controversial appointment of Peter Mandelson, a prominent Labour Party figure with documented ties to convicted sex offender Jeffrey Epstein, as the United Kingdom’s ambassador to the United States.

    Despite explicit warnings from multiple quarters, Prime Minister Starmer proceeded with the appointment of the 72-year-old political veteran in December 2024. The decision was strategically motivated by Mandelson’s perceived diplomatic charm and networking capabilities, particularly valuable as the UK sought to navigate potential trade tariffs under the incoming Trump administration.

    The appointment quickly unraveled when, in September 2025, email correspondence between Mandelson and Epstein surfaced, revealing their sustained relationship continued well after Epstein’s 2008 conviction for sex offenses involving a minor. Starmer promptly dismissed Mandelson from his diplomatic position on the eve of President Trump’s scheduled state visit to the UK.

    The crisis escalated dramatically in February 2026 when the US Justice Department released millions of documents related to Epstein. These files contained damning evidence that Mandelson had shared market-sensitive information with Epstein during the global financial crisis of 2009 while serving in Prime Minister Gordon Brown’s government. Additional revelations indicated Mandelson had tipped off Epstein about an imminent 500 billion-euro currency stabilization deal and received approximately $75,000 in payments from Epstein through accounts associated with Mandelson or his partner.

    Confronted with overwhelming evidence, Mandelson resigned from the Labour Party and relinquished his seat in the House of Lords to prevent ‘further embarrassment.’ British authorities subsequently launched a criminal investigation into Mandelson for alleged misconduct in public office.

    Prime Minister Starmer, appearing visibly shaken before Parliament, acknowledged Mandelson had ‘repeatedly lied’ about his connections to Epstein and apologized to Epstein’s victims for his administration’s failure to properly vet the appointment. The Prime Minister agreed to release all relevant documents concerning the appointment process and pledged to introduce legislation stripping Mandelson of his honorary title.

    The controversy claimed its first high-profile resignation when Morgan McSweeney, Starmer’s chief of staff, stepped down accepting full responsibility for recommending Mandelson’s appointment. While Scottish Labour leader Anas Sarwar called for Starmer’s resignation citing ‘too many mistakes,’ the Prime Minister secured crucial support from cabinet ministers and Labour lawmakers during a closed-door meeting, declaring his determination not to ‘walk away from my mandate and my responsibility to my country.’

  • French prosecutor searches for victims after a man is accused of abusing 89 minors over 55 years

    French prosecutor searches for victims after a man is accused of abusing 89 minors over 55 years

    French judicial authorities have taken the extraordinary step of publicly identifying a 79-year-old man accused of sexually assaulting 89 minors across multiple continents over a 55-year period, in what represents one of France’s most extensive child abuse investigations.

    Étienne Manteaux, Grenoble’s chief prosecutor, disclosed that Jacques Leveugle faces formal charges of aggravated rape and sexual assault against minors. The suspect has remained in pretrial detention since April 2025 following his initial investigation in February 2024.

    The breakthrough in this unprecedented case emerged from digital evidence—a comprehensive USB drive containing what prosecutors describe as 15 volumes of autobiographical writings. These documents, discovered by a family member and subsequently handed to law enforcement, allegedly detail sexual violations against boys aged 13 to 17 between 1967 and 2022.

    Manteaux explained his unusual decision to publicly name the suspect—a practice generally avoided in French judicial proceedings—as necessary to facilitate victim identification. “This name must be known because the goal is to allow possible victims to come forward,” he stated during a press briefing.

    Investigators established dedicated hotlines for potential victims after encountering difficulties in identifying individuals from the documents, which often contained incomplete identifying information. The global scope of the allegations spans numerous countries including Germany, Switzerland, Portugal, Morocco, Algeria, Niger, the Philippines, India, Colombia, and New Caledonia, where the suspect reportedly worked as an educator.

    In a disturbing development, prosecutors revealed the suspect has acknowledged two separate euthanasia-style killings within his family, prompting a parallel murder investigation. According to Manteaux, Leveugle admitted to suffocating his terminally ill mother and later his 92-year-old aunt under similar circumstances.

    The case emerges as France continues to grapple with the aftermath of the recent Pelicot sexual violence trial, with both investigations relying heavily on digital evidence to uncover long-hidden crimes.