A tragic incident unfolded in Louisville as a UPS cargo plane crashed during takeoff, resulting in the deaths of three individuals. Authorities have indicated that the death toll is expected to rise as rescue operations continue. The crash has left the city shrouded in smoke, with emergency teams working tirelessly at the scene. Preliminary reports suggest that the aircraft encountered difficulties shortly after departure, leading to the devastating accident. The Federal Aviation Administration (FAA) and National Transportation Safety Board (NTSB) have launched investigations to determine the cause of the crash. Local residents have expressed shock and grief, while officials urge caution as the situation develops.