No DNA matches on glove found in Nancy Guthrie case, police say

Pima County investigators have encountered a significant setback in the high-profile search for Nancy Guthrie. A glove, discovered roughly two miles from the 84-year-old’s residence and believed to be a critical piece of evidence, has failed to produce any identifying DNA matches in federal databases.

The item, recovered by authorities, is considered a potential match to one worn by an unidentified individual captured in doorbell surveillance footage from the evening of February 1st, the night Guthrie is suspected to have been abducted from her home against her will. The Pima County Sheriff’s Department submitted DNA evidence extracted from the glove for forensic analysis last Thursday.

However, processing through the FBI’s Combined DNA Index System (CODIS)—a comprehensive national database containing genetic profiles of convicted offenders, arrestees, and forensic evidence from unsolved crimes—returned no matching profiles. This result indicates the potential suspect does not have a prior criminal record that would have mandated their DNA be entered into the system, effectively leaving investigators without a clear suspect identity.

The disappearance of Nancy Guthrie, mother of ‘Today’ show co-anchor Savannah Guthrie, has triggered an extensive multi-agency investigation. Her family has maintained a relentless public campaign, issuing heartfelt pleas for any information leading to her safe return. Despite this latest forensic disappointment, authorities are continuing to pursue all active leads in the case.