In a significant move to address the rising costs of pharmaceuticals, US President Donald Trump has announced agreements with major drug manufacturers Eli Lilly and Novo Nordisk to reduce the prices of popular weight-loss medications. The deals, unveiled at the White House, aim to make obesity treatments more affordable for Americans, particularly those enrolled in Medicare and Medicaid. Under the new arrangements, consumers will pay between $245 and $350 per month for drugs like Wegovy and Zepbound, which are part of the GLP-1 class of medications used to treat diabetes and obesity. Without insurance, these drugs often cost over $1,000 monthly. The agreements will expand access to these medications for Medicare beneficiaries, with an estimated 10% eligible to pay just $50 per month. Medicaid enrollees will see phased access based on state participation. Additionally, Eli Lilly will benefit from a three-year tariff exemption as part of the deal. The Trump administration has also launched TrumpRx, a government-run website set to debut by January, where these drugs will be sold at discounted prices. Wegovy and Zepbound will initially cost $350 per month on average, dropping to $250 within two years. Eli Lilly’s orforglipron will be priced at $149 for the lowest dose, while Zepbound will start at $299, pending FDA approval. Health Secretary Robert F. Kennedy Jr. emphasized the importance of these agreements in combating obesity, which he termed the leading driver of chronic disease in the US. However, he stressed that medication alone is not a cure-all, advocating for lifestyle changes like diet and exercise. This initiative follows months of negotiations and pressure from the Trump administration, which has already secured similar deals with Pfizer, AstraZeneca, and EMD Serono.
标签: North America
北美洲
-

Engine fell off US cargo plane before deadly crash; death toll rises to 12
A catastrophic cargo plane crash in Kentucky has claimed the lives of 12 individuals, with investigators attributing the disaster to an engine fire and detachment during takeoff. The McDonnell Douglas MD-11, operated by UPS and en route to Hawaii, crashed shortly after departing from Louisville Muhammad Ali International Airport on Tuesday evening. The aircraft exploded into flames upon impact, devastating nearby businesses and leaving a fiery debris field nearly half a mile long. Louisville Mayor Craig Greenberg expressed profound sorrow over the rising death toll, while Kentucky Governor Andy Beshear described the incident as ‘heartbreaking’ and ‘unimaginable.’
The National Transportation Safety Board (NTSB) has launched a comprehensive investigation, with preliminary findings from airport footage revealing the left engine detaching during the takeoff roll. The flight data recorder and cockpit voice recorder, commonly known as black boxes, have been identified and will be sent to Washington for detailed analysis. The crash, reportedly the deadliest in UPS’s history, has prompted the company to suspend package sorting operations at its Louisville facility, which serves as its primary hub.
The aircraft, carrying approximately 38,000 gallons of fuel, narrowly avoided a major Ford assembly plant, averting an even greater catastrophe. Aerial footage of the crash site depicted a trail of debris and firefighters battling intense flames. The NTSB confirmed the plane was built in 1991 and later converted into a cargo aircraft. Boeing, which merged with McDonnell Douglas in 1996, has offered technical assistance to the NTSB. The incident has reignited concerns about the US air traffic control system, already strained by staffing shortages and aging equipment, following a series of fatal aviation accidents in recent years.
-

Dubai: 44,000 new homes to be ready in 2025; highest in 5 years
Dubai’s real estate market is poised for a significant milestone in 2025, with 44,000 new residential units expected to be completed—the highest number in five years. This surge in supply is a result of projects initiated during the post-pandemic period reaching their final stages, according to a recent analysis by Cushman & Wakefield Core. The consultancy highlighted that Dubai’s residential market is currently experiencing a robust supply cycle, with a substantial pipeline of projects nearing completion. In the third quarter of 2025 alone, over 7,800 units were delivered, with an additional 14,900 units anticipated in the fourth quarter. Prathyusha Gurrapu, Head of Research and Consultancy at Cushman & Wakefield Core, noted that the market is transitioning into a more balanced phase, where factors such as location and quality will increasingly influence performance. Prime areas are expected to remain stable, while secondary locations may adjust to the influx of new supply. Looking ahead, completions are projected to rise further in 2026, with over 69,000 units anticipated. This near-term supply reflects the volume of projects launched in recent years, coupled with strong demand driven by record population growth. However, the increased stock is likely to moderate price and rental growth, contributing to a more tempered market. According to property portal Bayut, established areas with strong infrastructure and sustained luxury demand will continue to thrive, while mid-market apartment areas may face saturation. Haider Ali Khan of Bayut emphasized that Dubai’s real estate market is maturing, with overall price growth moderating due to increased supply and measured investor sentiment. Data from Cushman & Wakefield Core revealed that city-wide residential sales prices reached Dh1,871 per sqft in Q3 2025, marking a 13% year-on-year increase. However, growth is slowing, particularly in the apartment segment. Villa communities such as Palm Jumeirah and Dubai Hills continue to outperform, supported by limited supply and resilient demand. As the market evolves, pricing will increasingly be driven by fundamentals such as location, quality, and developer profile.
-

US to cancel flights as longest government shutdown drags on
The United States is bracing for significant disruptions in air travel as the longest government shutdown in history continues to cripple federal operations. Transportation Secretary Sean Duffy announced a 10% reduction in flight capacity across 40 high-traffic air traffic areas, effective Friday. Major airports in Atlanta, Dallas, Los Angeles, and New York City are expected to bear the brunt of these cuts. The Federal Aviation Administration (FAA) confirmed the reductions, citing staffing shortages due to the ongoing shutdown. Over 60,000 air traffic controllers and Transportation Security Administration (TSA) officers are currently working without pay, raising concerns about increased absenteeism and potential chaos at check-in lines. The shutdown, which began after Congress failed to approve funding past September 30, has left 1.4 million federal workers either furloughed or working without compensation. House Speaker Mike Johnson warned that flight delays, initially at 5%, have now surged to over 50%, jeopardizing public safety. The impasse between Democrats and Republicans centers on healthcare spending, with Democrats demanding an extension of expiring insurance subsidies and Republicans insisting on immediate funding approval. Former President Donald Trump has intensified pressure on Democrats by threatening mass layoffs and targeting progressive priorities. Amid the crisis, the White House clarified its commitment to partial payments under the Supplemental Nutrition Assistance Program (SNAP), despite earlier threats to cut off aid.
-

US teacher shot by six-year-old student awarded $10m by jury
A former Virginia schoolteacher, Abigail Zwerner, who was shot by a 6-year-old student two years ago, has been awarded $10 million in damages by a jury. The incident, which occurred in January 2023 at Richneck Elementary School in Newport News, left Zwerner seriously wounded, requiring multiple surgeries. During her trial, Zwerner testified, ‘I thought I had died,’ highlighting the traumatic experience she endured. Zwerner filed a $40 million lawsuit against the school’s former assistant principal, Ebony Parker, alleging that Parker failed to act despite being warned that the child might have brought a gun to school. The jury found Parker’s inaction to be gross negligence. The court heard that Parker had been informed about the gun approximately 45 minutes before the shooting. Additionally, Zwerner had reportedly warned Parker about the child’s violent mood and threats against another student, to which Parker allegedly responded indifferently. Parker’s defense argued that she could not have foreseen the incident and that Zwerner exaggerated her injuries. Following the civil trial, Parker faces eight counts of felony child neglect, each punishable by up to five years in prison. The student’s mother was sentenced to nearly four years for child neglect and federal weapons charges. The student, who was not charged, is now in the care of a relative and attending a different school. This case underscores the ongoing issue of gun violence in the United States and the critical need for effective school safety measures.
-

Veteran South Indian actor Harish Rai, star of ‘KGF’ and ‘Om’, dies
The South Indian film industry is in mourning following the passing of veteran actor Harish Rai, celebrated for his iconic roles in the ‘KGF’ series and the film ‘Om’. Rai, who had been battling cancer, breathed his last on November 6, 2025. Known for his portrayal of Khasim chacha in the blockbuster ‘KGF’ franchise, Rai was a stalwart of Kannada cinema, with a career spanning decades and contributions to Tamil and Telugu films as well. Karnataka Deputy Chief Minister DK Shivakumar confirmed the news on his X account, expressing deep sorrow and paying tribute to the actor’s legacy. Shivakumar described Rai’s death as a significant loss to the industry, highlighting his memorable performances in films like ‘Hello Yama’, ‘KGF’, and ‘KGF 2’. Rai’s versatility and talent earned him widespread acclaim, making him a beloved figure in South Indian cinema. Beyond his iconic roles, he appeared in numerous popular Kannada films, including ‘Samara’, ‘Bangalore Underworld’, ‘Jodihakki’, and ‘Sanju Weds Geetha’. The film fraternity and fans alike have expressed their condolences, remembering Rai for his remarkable contributions to the art of storytelling. His passing marks the end of an era, leaving behind a legacy that will continue to inspire future generations.
-

Weekly quiz: Which supermodel turned her husband to stone for Halloween?
This week witnessed a series of notable events across the globe. In Georgia, Bella Culley, a pregnant British teenager, was released from prison, marking a significant moment in her life. Meanwhile, in Thailand, the Miss Universe competition experienced an unexpected walkout, adding drama to the prestigious event. On a more celebratory note, David Beckham was knighted by King Charles, a recognition of his contributions to sports and philanthropy. These events, though diverse, highlight the dynamic nature of global news. As we reflect on the past seven days, it’s essential to stay informed about the broader happenings that shape our world. For those keen on testing their knowledge, quizzes curated by Ben Fell offer an engaging way to recall and learn about recent events.
-

UAE identifies top reasons for traffic jams, plans new systems to curb congestion
The United Arab Emirates (UAE) is taking decisive steps to address its growing traffic congestion challenges, driven by a surge in private vehicle ownership and peak-hour bottlenecks. Speaking at the UAE Government Annual Meetings in Abu Dhabi, Minister of Energy and Infrastructure Suhail Al Mazrouei highlighted the urgency of the issue, noting that vehicle numbers on UAE roads are increasing at an annual rate of over eight percent—far exceeding the global average of two percent. This trend, coupled with overlapping school and work hours, has placed significant strain on the nation’s road networks, particularly between Dubai and the Northern Emirates. Commuters in these areas reportedly lose up to 460 hours annually to traffic delays, equivalent to 60 working days. To combat this, the UAE is implementing a multi-faceted strategy that includes road expansions, enhanced public transport integration, updated policies, and advanced smart-mobility technologies. A 24-hour integrated traffic-monitoring center is already analyzing congestion patterns and proposing targeted solutions. Additionally, the Dh50-billion UAE Railway Programme, set to launch passenger services by 2026, aims to strengthen connectivity between cities and reduce reliance on private vehicles. Officials believe these measures will ensure the UAE remains ahead of rising transport infrastructure demands as its population and economic activity continue to grow.
-

Boeing criminal case linked to deadly 737 crashes dropped
Boeing has successfully avoided a criminal charge in the United States related to two fatal 737 Max crashes, following a court decision to dismiss the case. The ruling, issued by Judge Reed O’Connor, came in response to a request from the U.S. government to drop the charge. While Judge O’Connor expressed personal disagreement with the decision, stating that it did not align with the public interest, he acknowledged that his concerns were insufficient to override the government’s proposal. This outcome represents a significant victory for Boeing, which had faced renewed legal scrutiny after the government accused it of violating a prior settlement tied to the crashes. The dismissal, however, was met with opposition from families of the victims, who sought to hold Boeing accountable through a trial. Attorney Paul Cassell, representing some of the families, announced plans to appeal the ruling, emphasizing the need to address perceived injustices. In his decision, Judge O’Connor criticized the government’s rationale for avoiding a trial as ‘unserious’ and expressed doubts about the new agreement’s ability to ensure public safety. Nonetheless, he deferred to the government’s presumed ‘good faith’ in the matter. The Department of Justice (DOJ) defended the agreement, highlighting extensive consultations with victims’ families and asserting that the resolution provides closure and immediate action from Boeing. Boeing, in turn, reaffirmed its commitment to the agreement and ongoing efforts to enhance safety and compliance. The case stems from two catastrophic 737 Max crashes in 2018 and 2019, which claimed 346 lives. Boeing had previously admitted to criminal fraud conspiracy charges in 2021, paying $2.5 billion in fines and compensation while pledging to improve safety standards. The case was reopened in 2023 following another incident involving a 737 Max, leading to accusations of breaching the original settlement. Under a new proposal in 2024, Boeing agreed to plead guilty, pay an additional $243 million fine, and accept court oversight. However, Judge O’Connor rejected this deal in December 2023, citing concerns over the selection of the monitor. The latest settlement, which dropped the criminal charge, requires Boeing to hire an independent compliance consultant and commit $1.1 billion, including penalties and compensation to victims’ families. Prosecutors justified the dismissal by citing Boeing’s ‘meaningful progress’ in anti-fraud and conspiracy programs.
-

‘AI president’: Trump deepfakes glorify himself, trash rivals
In an unprecedented move, former U.S. President Donald Trump has embraced artificial intelligence (AI) as a central tool in his political communication strategy. Since beginning his second term, Trump has flooded his Truth Social platform with hyper-realistic AI-generated content, portraying himself in grandiose roles while discrediting his political adversaries. These fabricated visuals, ranging from Trump as a crowned king to Superman, have captivated and deceived social media users, blurring the lines between reality and fiction. The White House has remained silent on whether Trump or his aides are behind these creations, but the impact is undeniable. Critics argue that this marks a dangerous escalation in the weaponization of AI for political gain. Trump’s posts have included absurd scenarios, such as a video of him piloting a fighter jet labeled ‘King Trump’ dumping waste on protesters, and another promoting the debunked ‘MedBed’ conspiracy theory. His use of AI has also targeted rivals, including former President Barack Obama and House Minority Leader Hakeem Jeffries, with racially charged imagery. Experts like Nora Benavidez of Free Press warn that such tactics distort reality and undermine public discourse. Meanwhile, California Governor Gavin Newsom has adopted a similar strategy, using AI-generated content to mock Republicans after recent Democratic victories. This trend raises critical questions about the ethical use of AI in politics and its potential to erode shared truths in society.
