A groundbreaking science exhibition, collaboratively developed by China and South Africa, is currently underway in Johannesburg, symbolizing a significant milestone in the bilateral partnership in science, technology, and cultural exchange. Titled ‘L.I.S.T.E.N Science Space,’ the exhibition is a joint initiative of the China Science and Technology Museum and South Africa’s Sci-Bono Discovery Center, occupying a 200-square-meter space within the latter’s premises. The exhibition is ingeniously divided into four thematic zones, each designed to stimulate innovative thinking, explore scientific principles embedded in traditional Chinese intangible cultural heritage, offer an immersive space exploration experience, and showcase the allure of bionic robot dogs. Beyond the exhibits, the event features regular open science classes, enabling visitors to engage in hands-on scientific activities. The China Science and Technology Museum has contributed its vast resources and expertise in science education, while the Sci-Bono Discovery Center has tailored the content to resonate with local audiences, exemplifying a model of cooperation aimed at fostering a shared future between China and Africa. The exhibition’s inauguration aligns with South Africa’s hosting of the G20 Summit, presenting a tangible demonstration of the fruitful collaboration between China and Africa to international delegates. Looking ahead, both nations intend to utilize this platform to expand bilateral cooperation through joint research, the creation of a digital resource library, and personnel exchanges, thereby sustaining the momentum for deepening China-Africa relations and enhancing mutual understanding.